The CorInnova Implantable Cardiac Assist System for Direct Cardiac Compression

The CorInnova cardiac compression device (CorInnova, Inc., Houston, TX, USA) is designed to provide direct biventricular support, increase output, and improve ventricular unloading in patients with heart failure. Placed within the pericardium surrounding both ventricles, has two concentric sets of thin-film polyurethane chambers: (1) inner (epicardial) saline-filled chambers that conform intimately epicardial surface, eradicating any gaps interface between heart; (2) outer air-filled cycled during systole negative pressure diastole, consistent physiological contraction relaxation. A superelastic, collapsible Nitinol frame gives structure, enables minimally invasive self-deployment, enhances diastolic filling. Preclinical testing been extremely promising, improvements output other parameters animal failure models. This potentially transformative technology moving rapidly toward first-in-human use. may an effective device-based solution for who currently have few or limited mechanical support options, including failure, those right are older, smaller size. It can be removed easily requires minimal maintenance. An important, unique feature this it provides assistance without blood contact need anticoagulation. particularly important contraindications anticoagulation due allergy, neurological bleeds, preexisting hemorrhage. No circulatory addresses these underserved heart-failure populations.